NorthStar Clinical Studies

Northstar Clinical Studies Underway

The Northstar Studies are global clinical studies being conducted to determine if the one-time gene therapy can decrease or eliminate the need for continued blood transfusions in people living with transfusion-dependent beta-thalassemia, while also being safe and well-tolerated.

Northstar-2 Study Now Enrolling

The study now enrolling, Northstar-2, is a Phase 3 global clinical study seeking to enroll patients who cannot make enough of the beta-globin portion of hemoglobin. See if someone you know may qualify.

Northstar-3 Study Now Enrolling

The Northstar-3 Study (HGB-212) is a Phase 3 global clinical study seeking to enroll patients who do not make the beta-globin portion of hemoglobin and who have a β0/β0 genotype. Based on the early data from the Northstar Study, it is believed that the current lentiviral vector technology may be more effective in decreasing the need of transfusions in people who have a β0/β0 genotype.